Use of nanotechnology in the diagnosis and treatment of coronavirus

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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JR_JCBIOR-2-2_002

تاریخ نمایه سازی: 9 آبان 1401

Abstract:

Coronavirus is a beta virus that has caused a worldwide pandemic since December ۲۰۱۹. Many treatments such as antiviral drugs, immunosuppressive drugs, neutralizing antibodies, and monoclonal antibodies have been tested on coronavirus disease ۲۰۱۹ (COVID-۱۹) that most of them were effective. Given that nanotechnology-based approaches have been successful in detection and treatment of viral systems such as human immunodeficiency virus (HIV), influenza A virus subtype H۱N۱ and Middle East respiratory syndrome coronavirus (MERS-CoV), they also seem to be effective in detecting and treating COVID-۱۹. Nanotechnology is used in various methods for early and rapid diagnosis of the disease. Nanoparticles can be used in products for the diagnosis, treatment and prevention of COVID-۱۹. These substances are very effective in the controlled delivery of antiviral drugs and biomolecules and they are also used in the manufacture of personal safety equipment, widely, and the production of anti-virus coatings for surfaces, air filters and the production of vaccines. In general, nanomaterial can play an important role in controlling the disease, based on strategies to prevent the virus from entering the host cell, inhibiting virus replication, virus delivery systems, and nano-based vaccines. Nanotechnology is a multidisciplinary tool that can offer a variety of solutions based on disease prevention, diagnosis and treatment strategies.

Authors

Elham Maghareh Abed

Department of Microbiology, Faculty of Biological Sciences, Islamic Azad University, North Tehran Branch, Tehran, Iran

Seyedeh Mahsan Hoseini-Alfatemi

Pediatric Infections Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Hoda Sabati

Biotechnology and Biological Science Research Center, Shahid Chamran University of Ahvaz, Ahvaz, Iran

Mohammad Amin Khajavi Gaskarei

Razi Clinical Research Development Unit, Guilan University of Medical Sciences, Rasht, Iran

Kourosh Delpasand

Razi Clinical Research Development Unit, Guilan University of Medical Sciences, Rasht, Iran

Marzie Ghasemi

Department of Biochemistry, School of Medicine, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran