Design of a novel enteric hard capsule formulation based on HPMCph biopolymer: Study of crucial capsule features
Publish Year: 1401
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
IRCCE10_025
تاریخ نمایه سازی: 16 آبان 1401
Abstract:
In this study, a novel enteric hard capsule formulation have been introduced for the first time. It is noteworthy that the employed pH-sensitive polymer is hydroxypropyl methyl cellolose phtalte noted as (HPMCph). To understand and address the important involved parameters for development of this capsule formulation, dissolution profile and surface properties of capsule have been investigated in detail. Furthermore, the effect of binder, gelling agent, plasticizer and surfactsnt on capsule features have been assessed in details. Based on the obtained results, the results are very suitable and certifies the utilization of this capsule for industrial applications.
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Authors
Ramezani kalmer
Iran Gelatin capsule mfg Co, ۳۳۵۱۷۷۳۴۱۵, Tehran, Iran.
Mohsen Mohammadi Haddadan
Iran Gelatin capsule mfg Co, ۳۳۵۱۷۷۳۴۱۵, Tehran, Iran.
Dariush Samandarian
Iran Gelatin capsule mfg Co, ۳۳۵۱۷۷۳۴۱۵, Tehran, Iran.
Maryam Azizi
Iran Gelatin capsule mfg Co, ۳۳۵۱۷۷۳۴۱۵, Tehran, Iran.
Mojgan Ghanbari
Iran Gelatin capsule mfg Co, ۳۳۵۱۷۷۳۴۱۵, Tehran, Iran.
Atefeh Sadjadi nia
Iran Gelatin capsule mfg Co, ۳۳۵۱۷۷۳۴۱۵, Tehran, Iran.