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Recent studies on antimicrobial and anticancer activities of saponins: a mini-review

Publish Year: 1401
Type: Journal paper
Language: English
View: 239

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JR_NMB-1-1_004

Index date: 4 January 2023

Recent studies on antimicrobial and anticancer activities of saponins: a mini-review abstract

Multidrug-resistant cancer cells and microbial pathogeneses remain the complicated hindrances in therapy for cancer and microbial infections. In addition, severe side effects from chemotherapy can result from conventional drugs. New formulations based on bioactive compounds isolated from medicinal plants may alleviate these side effects and increase antimicrobial activity. Saponins as surface-active triterpene glycosides can be synthesized by various plants (wild plants and cultivated crops such as soapbark trees and soapwort), lower marine animals, and some bacteria. Nano-formulations of saponins, particularly on a scale of <100 nm, can augment therapeutic effects in the body by overcoming some disadvantages of saponins, mainly potential damage to the intestinal mucosa and disruption of blood cells.

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Recent studies on antimicrobial and anticancer activities of saponins: a mini-review authors

Shokouh Amraei

Lorestan University of Medical Sciences, Khorramabad, Iran

Shirin Ahmadi

Department of Biology, Faculty of Science, Khorramabad, Lorestan University, Lorestan, Iran