The survey of Streptococcus agalactiae carriage in pregnant women and determination of antibiotics susceptibity pattern in Amol city

Background and Aim: Streptococcus agalactiae is one of the most important causes of  neonatal infection such as sepsis ,meningitis and pneuomonia. This study was peformed to determine the clonization rate and susceptibility patterns of these isolated bacteria among the population of pregnant women.. Materials and Methods: The Vaginal and rectal swabs were obtained from 100 pregnant  women attending Imam Ali Hospital and Qaem Polyclinic of Social Security of Amol in 2013. Isolated bacteria were identified and cofirmed by standard microbiological tests and PCR.Antimicrobial susceptibility patterns was performed by disk diffusion agar according to CLSI. Results: Among one hundred (100) pregnant women participated in this study, the carriage rate of S. agalactiae was 10%. All isolated S. agalactiae  were susceptible to penicillin, ceftriaxon, vancomycin, clindomycin, nitroforantoin and ampicillin. Conclusions: Due to the prevention strategies to reduce the S. agalactiae associated diseases, we recommend screening of all pregnant women for Streptococcus agalactiae between 35-37 weeks gestation with a vaginal and rectal swabs and determine the S. agalactiae antimicrobial susceptibility patterns.

The survey of Streptococcus agalactiae carriage in pregnant women and determination of antibiotics susceptibity pattern in Amol city Keywords:

Pregnant women , PCR , Streptococcus agalactiae , استرپتوکوکوس آگالاکتیه , زنان باردار , واکنش زنجیره ای پلی مراز