The Association of Dietary Inflammatory Index with the Risk of Peptic Ulcer: A Case-Control Study
Publish place: Journal of Nutrition and Food Security، Vol: 8، Issue: 3
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
View: 104
This Paper With 12 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JNFS-8-3_010
تاریخ نمایه سازی: 24 مرداد 1402
Abstract:
Background: Peptic ulcer disease (PUD) is a gastrointestinal ulcer caused by gastric acid. Aging, smoking and alcohol, stressful life, and family history are directly related to PUD. Oxidative stress and inflammation are the most important mechanisms involved in PUD. The aim of this study is to evaluate the association of dietary inflammatory index (DII) with the risk of PUD. Methods: In this case-control study, data from ۱۰۰ newly diagnosed peptic ulcer patients and ۱۵۰ healthy individuals were analyzed. DII was assessed based on dietary intake data collected through a ۱۷۴-item validated food frequency questionnaire (FFQ). To calculate DII, ۳۶ nutrients and food components were used after adjusting the energy intake. Adjusted odds ratios (OR) and ۹۵% confidence intervals (CI) regarding the association between DII and PUD risk were estimated by logistic regression. Results: The mean DII score in patients (۰.۴۳±۱.۸۸) was significantly higher than the mean DII in healthy individuals (-۲.۸۸±۲.۰۰) (P=۰.۰۰۵), i.e. patients had received more inflammatory diet. In the crude model of PUD, odds increased significantly in the third and fourth quartiles of DII score compared to the lowest quartile (OR of third quartile vs first quartile: ۲.۶۵, ۹۵% CI:۱.۲۷-۵.۵۲, respectively; and OR of fourth quartile vs first quartile: ۲.۳۳, ۹۵% CI:۱.۱۲-۴.۸۵, respectively; P- trend=۰.۰۰۱). After checking multiple potential confounders, OR in third and fourth quartiles remained high and there was no change in the results. Conclusions: These findings suggest that more pro-inflammatory diets, indicated by higher DII scores, may increase the risk of PUD. Therefore, anti-inflammatory diet may play a protective role against PUD.
Keywords:
Authors
Faezeh Fouladvand
Student Research Committee, Lorestan University of Medical Sciences, Khorramabad, Iran
Mehdi Birjandi
Department of Biostatistics and Epidemiology, Lorestan University of Medical Sciences, Khorramabad, Iran.
Sadegh Amiri Kia
Endoscopy Department of Shahid Rahimi Hospital, Lorestan University of Medical Sciences, Khorramabad, Iran
Ebrahim Falahi
Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran; ۵ Department of Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran..
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :