One Pot Synthesis of Highly Functionalized Tetrahydropyridines Using Nano-TiCl۲/cellulose as Biodegradable and Eco-Friendly Catalyst

Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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تاریخ نمایه سازی: 3 مهر 1402


TiCl۴/nano-cellulose as a biodegradable and eco-friendly Lewis acid catalyst was synthesized via reaction of nano-cellulose and TiCl۴. This catalyst was characterized and used for synthesis of asymmetric highly functionalized tetrahydropyridines via a five-component condensation reaction of p-substituted anilines, aldehydes and ethyl acetoacetate under solvent-free condition. Simple methodology, eco-friendly catalyst, clean procedure, easy work-up and high yields are some of the important advantages of this protocol.


Bi Bi Fatemeh Mirjalili

Yazd University

Sara Azad

chemistry department , yazd university

Abdolhamid Bamoniri

Departent of Organic Chemistry, Faculty of Chemistry, University of Kashan