Genetic Variations in Host Factors and their Critical Role on HCV Medication
Publish place: Research in Molecular Medicine، Vol: 5، Issue: 1
Publish Year: 1395
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_REMJ-5-1_002
تاریخ نمایه سازی: 22 دی 1402
Abstract:
Although standard treatments are nearly life-saving in hepatitis C patients, all patients equalldon’t respond to such medications. To achieve an efficient therapeutic response in all patients, medications should individually alter based on genetic factor variations. Hence, having more detailed knowledge of the affective factors on the disease promotion could help us to organize an appropriate regime to treat HCV patients. In order to review recent studies on HCV-related treatments, the data was collected from the clinical and molecular studies published during the last ۱۵ years in electronic databases such as PubMed, Google Scholar, Medline, Scopus and Web of Sciences. Thus, this literature reviews the recent clinical studies with the genetic-based aspects, especially those factors affecting the etiopathological and histological feature of hepatitis C, diagnostic genetic and viral affecting criteria as well as some effective treatment strategies.
Authors
Maryam Karkhane
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abdolrazagh Marzban
Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Hamed Esmaeil Lashgarian
Hepatitis Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran
Mohammad Reza Zali
Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
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