Elastase enzyme activity and stability under the influence of phenanthrene toxic compound using docking and TM and FTIR methods
Publish place: The fourth international conference on research findings in basic sciences and engineering sciences
Publish Year: 1402
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ENGCONGE04_004
تاریخ نمایه سازی: 8 بهمن 1402
Abstract:
Phenanthrene is a type of polycyclic aromatic hydrocarbons (PAHs) of organic pollutants, PAHs are mainly derived from human activities related to pyrolysis and incomplete combustion of organic matter. Air with a high concentration of PAHs causes many adverse effects on various types of organisms, including plants, birds and mammals.In this study, the activity and performance of elastase enzyme under the influence of phenanthrene were investigated through FTIR, TM (thermal stability) and docking methods. The results showed that phenanthrene has an effect on the secondary structure of elastase and this enzyme has become more unstable due to the effect of phenanthrene.
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Authors
Mahbubeh Abdellahi
Student , Department of Biology , Shahrekord University , Shahrekord , I ran
Sadegh Farhadian
Assistant Professor, Department of Biology , Shahrekord University , Shahrekord , Iran
Behzad Shareghi
Full Profesor, Department of Biology , Shahrekord University , Shahrekord , Iran