Comparing the Effect of Garlic and Lemon Mixture with Mucilage of Okra Pods to Prevent the Increase of Plasma Lipids in Ratus norvegicus alluvia

Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_IJHS-3-2_006

تاریخ نمایه سازی: 29 بهمن 1402

Abstract:

Background: Cardiovascular disease is one of the main causes of mortality in the world and is primarily caused by high blood lipids. This study aimed to compare the effect of garlic and lemon mixture with mucilage of the okra pods in preventing the increase of plasma lipids in male Ratus.Methods: This study was performed on ۳۴ Ratus norvegicus alluvia. The Ratus were randomly divided into two classes, which were further subdivided in three groups each. A class of Ratus received food mixed with market oils for ۶۰ days. Moreover, the Ratus in the treatment group received ۱۰% okra mucilage and the mixture of garlic and lemon as gavage for ۳ weeks. Data were analyzed by SPSS-۲۱ software. The Mann–Whitney nonparametric test was used to compare each pair of groups. A value of ۵% was considered as statistically significant.Results: Comparing the control group and the group receiving oil, we observed that lipid intake was effective and significantly increased the blood cholesterol in the oil group (p = ۰.۰۰۶). In Ratus receiving fatty foods, it was observed that treatment regimens reduced blood lipids. Moreover, a significant difference was observed between the two treatment groups, indicating a ۱۰% mucilage advantage in reducing blood lipids compared with other treatment groups.Conclusions: The results indicate that both treatments reduce blood lipids, but ۱۰% mucilage in Ratus with high blood lipids has better efficacy than garlic and lemon mixture in reducing blood lipids.Background: Cardiovascular disease is one of the main causes of mortality in the world and is primarily caused by high blood lipids. This study aimed to compare the effect of garlic and lemon mixture with mucilage of the okra pods in preventing the increase of plasma lipids in male Ratus. Methods: This study was performed on ۳۴ Ratus norvegicus alluvia. The Ratus were randomly divided into two classes, which were further subdivided in three groups each. A class of Ratus received food mixed with market oils for ۶۰ days. Moreover, the Ratus in the treatment group received ۱۰% okra mucilage and the mixture of garlic and lemon as gavage for ۳ weeks. Data were analyzed by SPSS-۲۱ software. The Mann–Whitney nonparametric test was used to compare each pair of groups. A value of ۵% was considered as statistically significant. Results: Comparing the control group and the group receiving oil, we observed that lipid intake was effective and significantly increased the blood cholesterol in the oil group (p = ۰.۰۰۶). In Ratus receiving fatty foods, it was observed that treatment regimens reduced blood lipids. Moreover, a significant difference was observed between the two treatment groups, indicating a ۱۰% mucilage advantage in reducing blood lipids compared with other treatment groups. Conclusions: The results indicate that both treatments reduce blood lipids, but ۱۰% mucilage in Ratus with high blood lipids has better efficacy than garlic and lemon mixture in reducing blood lipids.

Authors

Moussa Abolhassani۱

۱. Student Research Committee, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran.

Mohammad Hassan Basirinezhad۲

۲. Dept. of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran.

Pirasteh Norouzi۳*

۳. Dept. of Physiology, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.