A comprehensive review of CNS and PNS manifestations of SARS-CoV-۲ infection

The novel coronavirus (۲۰۱۹-nCoV, or COVID-۱۹) was, for the first time, detected in Wuhan city (China) in ۲۰۱۹. It was subsequently spread worldwide which resulted in a viral pandemic associated with high rate of mortality. Although this virus mainly affects the pulmonary system, it has already been reported that COVID-۱۹ could also affect the nervous system, either at the first stages of disease or during the illness progress. During COVID-۱۹ pandemic, numerous neurological complications corresponding to Central Nervous System (CNS) disorders such as giddiness, headache, unconsciousness, encephalitis and ataxia, as well as Peripheral Nervous System (PNS) disturbances including Guillain-Barre syndrome (GBS), skeletal muscle malfunction, hyposmia, hypogeusia and muscle pain, were reported. In this regard, further researches about neurological manifestations of COVID-۱۹ is suggested. Current review attempts to discuss various CNS and PNS manifestations of SARS-CoV-۲ virosis.

Keywords:

COVID-۱۹ , neurological manifestations , CNS , PNS , SARS-CoV-۲