Fe3O4/SiO2/(CH2)3N+Me3Br3–catalyzed solvent-free synthesis of five- and six-membered heterocycles

Functionalized magnetic core–shell nanoparticle [Fe3O4/SiO2/(CH2)3N+Me3Br3-] is prepared by coprecipitationmethod, characterized by transmission electron microscopy, FT-IR, X-ray diffraction, and vibrating samplemagnetometer. The catalytic activity of this nanoparticle was tested in the syntheses of imidazole, benzothiazole, andperimidine derivatives, under solvent-free conditions. The catalyst was readily recycled by the use of an external magneticfield and and could be reused five times without significant loss of activity or mass.

Keywords:

Magnetically retrievable , Grafting , Silica , Nano-hybrid , Heterocyclic synthesis