Vagifem is superior to vaginal Premarin in induction of endometrial thickness in the frozen-thawed cycle patients with refractory endometria: A randomized clinical trial
Publish Year: 1393
نوع سند: مقاله ژورنالی
زبان: English
View: 414
This Paper With 6 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_IJRM-12-6_007
تاریخ نمایه سازی: 16 شهریور 1395
Abstract:
Background: Embryo transfer to a developed endometrium is an important prognostic factor in frozen-thawed embryo transfer cycle outcome. Vaginalestrogen, such as Vagifem vaginal tablets and Premarin vaginal cream, is a regimen used for the patients with refractive endometria.Objective: Our objective was to compare the effects of Vagifem and Premarin onthe endometrial thickness of the patients with refractive endometria.Materials and Methods: In this randomized clinical trial, 30 patients with refractive endometria in frozen-thawed embryo transfer cycles received Vagifemvaginal tablets and 30 women received Premarin vaginal cream. Endometrial thickness was measured on the 14th day of drug administration.Results: Comparing the endometrial thicknesses of the two groups showed that the endometria of the Vagifem group was significantly thicker than that of the Premaringroup (5.93±0.38 vs. 6.74±0.32; p<0.001). Conclusion: Vagifem is superior to Premarin in induction of endometrial thickness in frozen-thawed embryo transfer cycles in the patients with refractive endometria.
Keywords:
Authors
Jaleh Zolghadri
Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Department of Obstetrics and Gynecology, Shiraz University of Medical Sciences, Shiraz, Iran
Hossein Haghbin
Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Nasrin Dadras
Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Shabnam Behdin
Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran