Design and Characterization of Biocompatible Polymer, PMBN, as a New Carrier for Drug Delivery Systems (DDS)

To develop a new polymer with a wide range of applications, a water-soluble amphiphilic phospholipid polymer (PMBN) was specially designed for preparation of nanoparticles which will be conjugated with ligands and drugs. PMBN was prepared by random copolymerization of three monomers which are 2-methacryloyloxyethyl phosphorylcholine (MPC), n-butyl methacrylate (BMA), and pnitrophenylester bearing methacrylate (MEONP). So, the mentioned polymer could simulate membrane cells conditions, and can be used as a great career for nano-biosensers and DDS

Keywords:

PMBN , MPC , BMA , MEONP , DDS