Synthesis of a New Dithiocarbamate Compound and Study of Its Biological Properties

Dithiocarbamates (DTC) are well known compounds to bind strongly and selectively to many metal ions, so in the past few years self-assembly directed by metal–dithiocarbamate coordination have emerged as a useful supramolecular methodology for the preparation of macrocycles, cages, catenanes, and nanoparticles. Most of applications are based on complexation properties of DTC ligands with metal ions, especially with transition metal ions. DTC ligands readily form chelates with all transition metal ions through its two donor sulfur atoms. In this research a new dithiocarbamate compound was synthesized and characterized using elemental analyses, FT-IR, NMR. The antibacterial activities of synthesized compound were studied against two Gram-negative species, Escherichia coli, Klebsiella pneumoniae and two Gram-positive species, Staphylococcus aureus and Bacillus subtilis and, for in vitro antifungal activity against, Candida albicans, Aspergillus flavus, Aspergillus nigar

Keywords:

Antibacterial activity , Synthesis , Dithiocarbamate