Compare Of The Survival And Apoptosis Of Breast Cancer Cells Under The Influence Of Crab Shell Extract
Publish place: 11th International Breast Cancer Congress
Publish Year: 1394
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ICBCMED11_055
تاریخ نمایه سازی: 21 اردیبهشت 1397
Abstract:
Introduction: Breast cancer is considered the most common cancer among women worldwide and Iranian women. The use of chemotherapy has many side effects. According considered to traditional, herbal and marine treatments. In this article was studied crab shell extract on breast cancer cell line MCF7. Materials and Methods: Crab shell was prepared and extracted. The extract were prepared at doses of 100, 200, 400, 800 and 1000 μg/ml. The crab shell extract dosedependent survival of breast cancer cells and decreased time. The greatest viability cell was reported in 1000 μg/ml and within 72 hours. Results: These results were confirmed for both Trypan blue and MTT method. Apoptosis of breast cancer cells increased in a dose-dependent within 72 hours. So Receipted within 72 hours to about 20 percent by 1000 μg/ml. Conclusion: Crab shell extract reduced cancer cell survival and increased apoptosis of cancer cells. So without side effect can be effective in improving the cancer.
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Authors
Leila Rezakhani
Fertility and infertility Research Center, University of Medical Sciences Kermanshah, Iran
Pegah Mirzapour
Fertility and infertility Research Center, University of Medical Sciences Kermanshah, Iran
Mohammad Rasool Khazaei
Fertility and infertility Research Center, University of Medical Sciences Kermanshah, Iran
Mozafar Khazaei
Fertility and infertility Research Center, University of Medical Sciences Kermanshah, Iran