The Role of Exosome On Male Infertility

Backgournd: During the past decade, miRNAs have been found to perform a pivotal role in various biologic processes, including development ,cell growth .and differentiation .Several studies report testicular-expressed miRNA changes depending on the stage of spermatogenesis. Method: All papers on the effect of exosome on male infertility by semen analyies indexed in databases pubMed, and Wiley Library and such journals as Science Direct and Springer without any time limit were explored. At first 117 relevantpapers were found and finally 5 ones were chosen based on inclusion criteria of present study. Finding: Exosome will have a good effect on semen such as: higher sperm motility, prolong effective survival time, improve sperm plasma membrane integrity increase total antioxidant capacity (T-AOC) activity and decrease malondialdehyde content. Conclusion: there are not enough research on this title to exactly recognize the effect of exosome on male infertility.

Keywords:

Exosome , Male Infertility , Semen Analysie