Publisher of Iranian Journals and Conference Proceedings

Please waite ..
CIVILICAWe Respect the Science
Publisher of Iranian Journals and Conference Proceedings
عنوان
Paper

The study of effect of Nalidixic acid in embryonic weight and organ development in mice

تعداد صفحات: 2 | تعداد نمایش خلاصه: 169 | نظرات: 0
سال انتشار: 1395
کد COI Paper: ACPLMED18_047
زبان Paper: Englishglish
نسخه کامل Paper در کنفرانس ارائه نشده است و در دسترس نیست.

مشخصات نویسندگان Paper The study of effect of Nalidixic acid in embryonic weight and organ development in mice

Mehdi Ahmadifar - Department of Embryology at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran
Saba Eskandari - Paramedical faculty, Borujerd Branch, Islamic, azad, university, Borujerd, Iran
Nazila Vahidi eyrisofla - Department of Biology, Damghan Branch, Islamic Azad University, Semnan, Iran
Elias Rajablou - Department of Embryology at Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

چکیده Paper:

Introduction:Nalidixic acid used in the treatment of uncomplicated urinary tract infections caused by Gram-negative bacteria, Except Pseudomonas spp. Nalidixic acid is ananti-bacterial compound that destroys sensitive bacteria in the urinary tract by stopping the production of essential proteins needed by the bacteria to survive. The aim of this study is to evaluate the effects of this drug on weight and mouse embryonic organ development. Material and method: In this study the effect of Nalidixic acid in embryonic weight and organ development in mice checked out in two groups and all of them was pregnant. Each group consisted of 10 mice, One of groups was the control and the treatment group get 200mg/kg of Nalidixic acid Intraperitoneal on eight day of pregnancy. On the thirteenth day embryo, the fetus removed from the uterus and examinedmacroscopically and microscopically. Result: The Nalidixic acid cause decrease in fetus weight and delays in the development of mice embryonic limb protrusions in the ventral lateral region fetus. Average weight in control group was 0/091 gr and in treatment group was 0/027 gr, significant difference was seen between the control group and the experimental group (P≤0/05). Conclusion: Decreased fetal weight and cause deformities in limbs mainly due to the ravages of Nalidixic acid by reducing proliferation of blood vessels and poor nutritional status of the fetus. Nalidixic acid cause mutations in the 10-5 methylene hydrofolate reducytase enzyme and subsequently weight loss and limb malformations observed.

کلیدواژه ها:

Nalidixic acid, Mice, Fetus

کد Paper/لینک ثابت به این Paper

برای لینک دهی به این Paper می توانید از لینک زیر استفاده نمایید. این لینک همیشه ثابت است و به عنوان سند ثبت Paper در مرجع سیویلیکا مورد استفاده قرار میگیرد:

https://civilica.com/doc/797246/

کد COI Paper: ACPLMED18_047

نحوه استناد به Paper:

در صورتی که می خواهید در اثر پژوهشی خود به این Paper ارجاع دهید، به سادگی می توانید از عبارت زیر در بخش منابع و مراجع استفاده نمایید:
undefined, undefined و undefined, undefined و undefined, undefined و undefined, undefined,1395,The study of effect of Nalidixic acid in embryonic weight and organ development in mice,هجدهمین همایش سالانه و اولین همایش بین المللی آسیب شناسی و طب آزمایشگاه,Tehran,,,https://civilica.com/doc/797246

در داخل متن نیز هر جا که به عبارت و یا دستاوردی از این Paper اشاره شود پس از ذکر مطلب، در داخل پارانتز، مشخصات زیر نوشته می شود.
برای بار اول: (1395, Ahmadifar, Mehdi؛ Saba Eskandari و Nazila Vahidi eyrisofla و Elias Rajablou)
برای بار دوم به بعد: (1395, Ahmadifar؛ Eskandari و Vahidi eyrisofla و Rajablou)
برای آشنایی کامل با نحوه مرجع نویسی لطفا بخش راهنمای سیویلیکا (مرجع دهی) را ملاحظه نمایید.

Research Info Management

Certificate | Report Paper

Export Citation info of this Paper to research management softwares

علم سنجی و رتبه بندی Paper

مشخصات مرکز تولید کننده این Paper به صورت زیر است:
نوع مرکز: research center
تعداد مقالات: 5,344
در بخش علم سنجی پایگاه سیویلیکا می توانید رتبه بندی علمی مراکز دانشگاهی و پژوهشی کشور را بر اساس آمار مقالات نمایه شده مشاهده نمایید.

New RelatedPapers

Share this paper

WHAT IS COI?

COI is a national code dedicated to all Iranian Conference and Journal Papers. the COI of each paper can be verified online.

Support