Synthesis and characterization of CdO/GrO nanolayer for in vivo imaging
Publish place: Nanomedicine Journal، Vol: 4، Issue: 3
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_NAMJ-4-3_008
تاریخ نمایه سازی: 18 تیر 1398
Abstract:
Objective(s): Nanomaterials are playing major roles in imaging by delivering large imaging payloads, yielding improved sensitivity. Nanoparticles have enabled significant advances in pre-clinical cancer research as drug delivery vectors. Inorganic nanoparticles such as CdO/GrO nanoparticles have novel optical properties that can be used to optimize the signal-to-background ratio. This paper reports on a novel processing route for preparation of CdO/GrO nanolayer and investigation of its optical properties for application in in vivo targeting and imaging.Materials and Methods: Nanostructures were synthesized by reacting cadmium acetate and graphene powder. The effects ofdifferent parameters such as power and time of irradiation were also studied. Finally, the efficiency of CdO/GrO nanostructures as an optical composite was investigated using photoluminescence spectrum irradiation. CdO/GrO nanostructures were characterized by means of X-ray diffraction (XRD), atomic force microscopy (AFM), scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) and photoluminescence (PL) spectroscopy.Results: According to SEM images, it was found that sublimation temperature had significant effect on morphology and layers. The spectrum shows an emission peak at 523 nm, indicating that CdO/GrO nanolayer can be used for in vivo imaging.Conclusion: The estimated optical band gap energy is an accepted value for application in in vivo imaging using a QD–CdO/GrO nanolayer.
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Authors
Abbas Pardakhty
Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
Mohammad Mehdi Foroughi
Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran
Mehdi Ranjbar
Young Researchers and Elite Club, Kerman Branch, Islamic Azad University, Kerman, Iran
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