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Paper
Title

Expression EZH2 in Epithelial and Stromal Cells in Breast

Year: 1398
COI: ACPLMED21_084
Language: EnglishView: 218
نسخه کامل این Paper ارائه نشده است و در دسترس نمی باشد

Authors

Hossein Bahrami Moqadam - Medical Student, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
Hamid Yazdaninejad - B.S Student in Anesthesiology, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
Reza Abouali - B.S Student in Medical Laboratory Science, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran
Reza Khedri - Medical Student, Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran

Abstract:

Background: Enhancer zester homolog 2 (EZH2) is a polycarbonate protein involved in stem cell and carcinogenesis. EZH2 is an oncogenic factor in breast cancer; increased EZH2 expression is associated with metastasis. The purpose of this study is Investigating Expression EZH2 in epithelial and stromal cells in breas Methods: This study is a systematic review article by surveying articles of databases and credible scientific websites include Science Direct, PubMed, scopus, and with keywords was EZH2, Breast cancer, pathology conducted during 2000 - 2018.Results: Healthy women with high EZH2 expression and low estrogen receptor (ER) expression in epithelium had a high risk of breast cancer; also woman with phyllodes tumor (PT) with high EZH2 expression in Stroma, was significantly associated with stromal overgrowth atypia, hypercellularity, and mitoses, grade of phyllodes tumor (PT) and all features of malignant PT.Conclusions: These results suggest that expression EZH2 in both of the breast epithelium of healthy women and the breast stroma of women with phyllodes tumors, increases the risk of malignancy.

Keywords:

Paper COI Code

This Paper COI Code is ACPLMED21_084. Also You can use the following address to link to this article. This link is permanent and is used as an article registration confirmation in the Civilica reference:

https://civilica.com/doc/951650/

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Bahrami Moqadam, Hossein and Yazdaninejad, Hamid and Abouali, Reza and Khedri, Reza,1398,Expression EZH2 in Epithelial and Stromal Cells in Breast,The 21st Annual Congress and the 4th International Congress of Pathology and Laboratory Medicine and The 8th Meeting of the Iranian Division of International Academy of Pathology (IAP)1,Tehran,https://civilica.com/doc/951650

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Type of center: علوم پزشکی
Paper count: 3,035
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