Synthesis and characterization of (Fe3O4@ kryptofix @ Ni) as aheterogeneous nanocatalyst and using its catalytic efficacyor in the synthesis of 2,3-dihydroquinazolin-4(1H)-ones

The use of nanomaterials as support in heterogeneous catalysis is a growing field of research1. Due to their high surface/volume ratio, nanoparticles (NPs) as a supporting material provide the benefit of an increased active surface area, which allows for increasing reaction rates. NPs are now often considered as a bridge between heterogeneous and homogene catalyses2 . Magnetic nanoparticles (mNPs) have attracted lot of interest in recent years in a wide range of disciplines due to their unique properties. They have been studied for example as nanofluids, in environmental remediation, in targeted drug delivery, in sensor applications, in imaging, in hyperthermia, and of course in catalysis3. Herein, In our studies on application of new heterogeneous and recoverable catalysts in organic transformations, we decided to prepare a novel heterogeneous catalyst (Fe3O4@ kryptofix @ Ni), and studied its application as in the synthesis 2,3-dihydroquinazolin-4(1H)-ones.The details of the synthesis 2,3-dihydroquinazolin-4(1H)-ones preparation procedure are presented by the concise route outlined in Fig 1.

Keywords:

Nanocatalyst , Ni-kryptofix[ , 2 , 2 , 2] complex , 2 , 3-Dihydroquinazolin-4(1H)-one.