Synthesis of 3-(4-((2-(trimethylsilyl)ethynylthio) methyl) phenyl) cyclo propane -1,1,2,2-tetracarbonitrile in different temperature conditions

Organosilicon compounds are widely encountered in commercial products. Most common are drug structures has been used to improve pharmacological potency, to modify selectivity toward a given target, to change metabolic rates, and to increase lipophilicity. Lipophilicity can provide several physiological benefits, including increased bioavailability and tissue and cell penetration Others important uses include agricultural plant control adjuvants such as herbicides and fungicides. 1–3

Keywords:

Ethyl cyanoacetate , One-pot reaction , 3-Alkyl-3-(bromomethyl)-1 , 2-dipropionylcyclopropane-1 , 2-dicarbonitrile , Cyanogen bromide.