Synthesis and characterization of new derivatives of iminosulfathiazoles
Publish place: 27th Iranian Seminar on Organic Chemistry
Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ISOC27_355
تاریخ نمایه سازی: 19 اسفند 1399
Abstract:
Sulfonamides are a class of antibiotics that have many applications on medicinal. Sulfa drugs have a sulfonamide functional group. Sulfathiazole is one of the most important sulfa drugs that has antibacterial and antimicrobial properties and it can be effective in the treatment of viral and bacterial diseases.1 Azo compounds have attracted much attention in both academic and applied research due to their versatile application in various fields, such as dyeing textile fiber, and advanced application in high technology areas such as laser, liquid crystalline displays, electro-optical devices, and ink-jet printers.2-5Here, the reaction between sulfathiazole and various azo compounds was performed via the imine bond (Fig.1).Then the synthesized products were isolated, purified and the structures of the newly synthesized hybrid molecules were characterized by TLC, M.P., FT-IR, 1H NMR, and 13C NMR. Antibacterial, antioxidant, anticancer properties and other biological properties will also be considered.
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Authors
Fatemeh Amouee,
Department of Chemistry, Faculty of Science, University of Guilan, Rasht, Iran
Nosratollah Mahmoodi
Department of Chemistry, Faculty of Science, University of Guilan, Rasht, Iran
Meysam Pasandideh Nadamani
Department of Chemistry, Faculty of Science, University of Guilan, Rasht, Iran