Design, fabrication and catalytic study of OMS-MIL-100(Fe) as an Efficient Green Catalyst for the aza-Michael Reaction

Porous coordination polymer as metal-organic frameworks (MOFs) have attracted significant attention during the past decade as promising nanoporous hybrid material for their potential application in gas storage and separation, sensors, drug delivery and catalysis 1, 2. Recently, the aza-Michael reaction is a prominent reaction for forming carbon-nitrogen bond in synthesis of β-amino carbonyl/cyano compounds 3 and it was widely used as key reaction in synthetic chemistry and synthesis of antibiotics, anticancer, drugs and natural product 4. Herein, we synthesized of a high porous open metal site MOFs of MIL-100(Fe) with new polygonal morphology as a suitable, efficient, and heterogeneous catalyst for the aza-Michael reaction Fig 1. Efficient transformation, mild condition, easy product isolation and the potential high recyclability of the organocatalyst are the key feature of this protocol.

Keywords:

Metal-organic framework , OMS-MIL-100(Fe) , Organocatalyst , Aza-Michael reaction.