synthesis of substituted quinolines under solvent -free conditions

A synthesis of quinoline derivatives is describen via reaction between haloketone , acetylenic dicarboxylate , and isatin under solvent free conditions , in the absence of haloketone the reaction leads to functionalized quinolines with the same esteric groups in 2,3,and 4-positions

Keywords:

quinolines , isatin , acetylenedicarboxylates , haloketones