The MostWell - known Markers of CSCs and Their Role in Growth of Tumors, Drug Resistance and Metastasis

The capability of cancer cells including tumor initiation, maintenance, and extension is associated with cancer stem cells. The substantialfeatures of CSCs are self - renewal and pluripotency. Therapeutic resistance of CSCs can result in cancer recurrence andfailure of cancer treatment. Isolation and characterization of CSCs are required for targeted cancer therapies. CSCs can be distinguishedand separated by surface markers. In this review, after definition of CSC hypothesis, different markers of CSC are introduced.The information about CSC markers provides promise for better isolation and more effective CSC-targeting therapeutic in future.

The MostWell - known Markers of CSCs and Their Role in Growth of Tumors, Drug Resistance and Metastasis Keywords:

Cancer , Stem Cells , Markers

The MostWell - known Markers of CSCs and Their Role in Growth of Tumors, Drug Resistance and Metastasis authors

Mohammad Javad Dehghan Esmatabadi

Malek - Ashtar University of Technology, Tehran, Iran

Fatemeh Movahedi Motlagh

Cellular and Molecular Research Center, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran- Department of Medical Genetics, Tehran University of Medical Sciences, Tehran, Iran

Azadeh Etemadzadeh

Institute of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran

Samira Hajigholami

Department of Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran

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علوم پزشکی > سرطان

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https://civilica.com/doc/1500652

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JR_JHGG-2-1_001

Index date: 21 August 2022

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Dehghan Esmatabadi, Mohammad Javad and Movahedi Motlagh, Fatemeh and Etemadzadeh, Azadeh and Hajigholami, Samira,1396,The MostWell - known Markers of CSCs and Their Role in Growth of Tumors, Drug Resistance and Metastasis,https://civilica.com/doc/1500652

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Scientometrics

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Ranking of Malek-Ashtar University of Technology

Type of center: دانشگاه دولتی

Paper count: 12,348

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