A review on ۵۸S bioactive glass and its composite coatings onsubstrates utilized in tissue engineering: Applications and properties

In the present study, a comprehensive review of the bio-applications and properties of ۵۸S bioactive glass(۵۸S BG) with a composition of ۶۰% SiO۲ - ۳۶% CaO - ۴% P۲O۵ as a coating on different substrates wasperformed. The best bioactive behavior among bioceramics is related to BG. BG has the ability to bonddirectly with bone tissue and facilitate the repair and regeneration of bone tissue. One of the limitations ofBG is its low mechanical properties, which has led researchers to utilize these materials as bioactivecoatings. In addition, the use of BG composite coatings with additive components can enhance themechanical properties of the coating and increase the biocompatibility of the substrate. Coating techniques,In-vitro bioactivity and biocompatibility of ۵۸S BG on substrates applied in tissue engineering are amongthe issues that have been investigated in this review work. Based on the collected results, it can be statedthat ۵۸S BG and its composite coatings can be considered as promising options to enhance thebiocompatibility, bioactivity and mechanical properties of the substrates used in tissue engineeringapplications.

Keywords:

۵۸S bioactive glass , Bioceramic , Coating , Bone tissue , Biocompatibility