Sequential HCoV-HKU۱ and SARS-CoV-۲ Infections, a Case Report

In the SARS-CoV-۲ pandemic, the seasonal viral respiratory infections had a minimum prevalence due to public health precautions to reduce the risk of getting Coronavirus Disease ۱۹ (COVID-۱۹). There have been reports of COVID-۱۹ coinfection with influenza, respiratory syncytial virus (RSV), and seasonal coronaviruses during the pandemic. Here, we report a case in which the patient had sequential respiratory infections of human coronavirus HKU۱ (HCoV-HKU۱) and SARS-CoV-۲ in a fully vaccinated, healthy person. It should be noted that other seasonal coronaviruses that could cause symptomatic RTIs might be misdiagnosed clinically with COVID-۱۹. Hence, we highly recommend monitoring and follow-up of symptomatic patients with negative SARS-COV-۲ RT-PCR results.

Keywords:

SARS-CoV-۲ , COVID-۱۹ , HCoV-HKU۱ , Coronaviruses , Sequential infection