Synthesis of the Novel Cyanocoumarin Derivatives Based onHeterocyclic Ketene Aminals

An efficient and concise method was developed for access to cyanocoumarins derivatives through a one-pot four-component protocol from diveres diamines, l,l-bis(methylthio)-2-nitroethen, alkyl cyanoacetate and salicylaldehyde. Green solvent, short reaction time, easy purification and free-base and catalyst are key feature of this protocol in this reaction.

Keywords:

Cyanocoumarins , HKAs , Catalyst-free , Green solvent