Determination of Cefixime in aqueous solution using multiwalled carbon nanotubes solid- phase extraction cartridge

one of the most important chemical properties of carbon nanotubes is having a hydrophobic surface, and because of that many compounds and materials can be retained on the surface of these nano structures. In this study, by using this feature of carbon nanotubes, their ability in adsorption of cefixime at trace amount from aqueous solution has been tested. Samples were strongly adsorbed by carbon nanotubes and acceptable recoveries were obtained. Analyses of samples were done by high performance liquid chromatography and UV. Limit of detection of cefixime under optimum conditions is ranged between 0.15-0.2μg/ml. recoveries of spiked sample analysis ranged from 86.8% to 88.4%.

Keywords:

Carbon nanotubes , Solid-phase extraction , High performance liquid chromatography , Cefixime