THE EFFECT OF RAMADAN FASTING ON PRO-OXIDANT AND ANTI-OXIDANT BALANCE IN PATIENT WITH NON-ALCOHOLIC FATTY LIVER DISEASE

Background and Aim: Ramadan is a famous month in the Islamic calendar which people abstain from eating, drinking, and smoking from sunrise to sunset. This study was performed to investigate the effects of Ramadan fasting on Pro oxidant And Anti-oxidant Balance. Methods: Overall, 50 patients with NAFLD, aged between 18 and 65 years, during June-July 2014 (Islamic calendar: 25 Shaban-8 Dhul Al-Qi’dah 1435) in Mashhad, Iran were recruited in this study. One week before Ramadan, 10 cc venous blood samples were drawn after 8-10 hours of fasting; the same procedure was undertaken at the end of Ramadan (27th day). Some portions of serum samples were used immediately to measure pro-oxidant-antioxidant balance. Results: The results have indicated that significant decrease in oxidative stress level (P value< 0.01). Moreover, gender did not have any significant relationship with changes in oxidative stress level. Conclusion: It seems that Ramadan fasting have a significant effect on oxidative and pro-oxidant-antioxidant balance in Non-Alcoholic Liver patients; however, further studies are required to confirm this results.

Keywords:

Fatty liver , Ramadan fasting , Pro-oxidant and Anti-oxidant Balance