Molecular diagnosis of class 1 integrons in Acinetobacter baumannii strains isolated from patients admitted in hospitals of Sari

Acinetobacter bumannii is opportunistic, gram-negative,aerobic, and non-fasting. The increasing resistance to the latest anti-dementia and high environmental resistance has made it difficult to control and eradicate this bacterium. The resistance pattern of this bacterium varies from region to region. Due to the increased mortality in patients, determining this pattern for It is necessary to determine the strategy of coping with this bacterium and the optimal use of antidepressants. Therefore, the aim of this study is to investigate the Class II Intronic molecular detection in A. berumani strains.This study was performed on 28 isolates of A. bumanni isolated from patients hospitalized in burns and infectious wards in Imam, Zare and Shafa Hospitals of Sari in the 6-month period of Bahman 95 to Tir 96. The antidepressant susceptibility of isolates was determined by disc diffusion agar method. The presence of Class 1 integrin was investigated by PCR method.In this study, the highest resistance to amikacin (95%) and the highest susceptibility to cefotaxime (85%) was observed. Class, I incontinence was 75% among strains isolated.In this study, high resistance to different classes of antidepressants in isolates and the high prevalence of class 1 integron was observed. Statistical analysis also revealed the relationship between Class 1 integron and drug resistance in these strains

Keywords:

Acinetobacter baumannii , Antibiotic resistance , Integrons