Synthesis and Antibacterial Activity of a New Bipyridyl Complex

The Schiff base molecules are a significant category of organic compounds with biologicalactivities such as antitumor, antifungal, antibacterial, antidiabetic and anthelmintic properties[1-3]. El-Sonbati and his colleagues [4] investigated the synthesis and characterization ofCu(II), Co(II), Ni(II) and Cd(II) complexes with 3-[(2-hydroxy-3-methoxybenzylidene) hydrazo]-1,3-dihydroindol-2-one ligand. The ligand and cadmium (II) complex exhibited goodantibacterial properties against Staphylococcus aureus bacterium.In this study, the synthesis, characterization and structure determination of a cadmium (II)complex with schiff base ligand of 2,5-bis(3-pyridyl)-3,4-diaza-2,4-hexadiene (3-bpdh) wasreported. The antibacterial activity of the ligand and the complex against the Gram-positivebacterium of Staphylococcus aureus is evaluated using disk diffusion method. The results representedthat the cadmium(II) acetate had the highest antibacterial activity in comparison toother compounds. Figure 1 shows the structure of complex with this Schiff base ligand.