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Burden of Congenital Factor XIII Deficiency in Iran

Publish Year: 1396
Type: Journal paper
Language: English
View: 328

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Document National Code:

JR_SBMU-2-3_005

Index date: 25 February 2020

Burden of Congenital Factor XIII Deficiency in Iran abstract

Congenital factor XIII (FXIII) deficiency is a rare coagulopathy with the highest incidence in Iran. Iranian patients with FXIII deficiency (FXIIID) presented high rate of bleeding episodes, some of them are major cause of disability and mortality among these patients. Hemarthrosis and intracranial hemorrhage (ICH) can affect activity and social productivity of patients. ICH, recurrent miscarriage and umbilical cord bleeding are the major cause of mortality. Hematoma, and prolonged menstrual bleeding as well as post-surgical bleeding are other significant bleeding in Iranian patients with FXIIID. Present of severe life threatening bleeding episodes and other notable bleedings, can significantly reduce working activities and social productivities of patients. Although Iranian patients with FXIIID, experienced significant diseases related complications, early diagnosis accompany by appropriate therapeutic regimes can prevent most of these problems.

Burden of Congenital Factor XIII Deficiency in Iran Keywords:

Burden of Congenital Factor XIII Deficiency in Iran authors

Akbar Dorgalaleh

Department of Hematology and Blood Transfusion, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran

Huda Motlagh

Student Research Committee, Department of Hematology and Blood Transfusion, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran

Shadi Tabibian

Department of Hematology and Blood Transfusion, School of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran

Majid Naderi

Department Of Pediatrics Hematology & Oncology, Ali Ebn-e Abitaleb Hospital Research Center For Children AndAdolescents Health [RCCAH], Zahedan University of Medical Sciences, Zahedan, Iran