One pot aqueous media synthesis of 1,3-oxazine derivatives catalyzed by reusable nano-Al2O3/BF3/Fe3O4 at room temperature
Publish place: 27th Iranian Seminar on Organic Chemistry
Publish Year: 1398
نوع سند: مقاله کنفرانسی
زبان: English
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شناسه ملی سند علمی:
ISOC27_422
تاریخ نمایه سازی: 19 اسفند 1399
Abstract:
The distinctive aspect of multi-component reactions (MCRs) is that the products contain all parts of substrates, creating almost no by-products. So, the applications of MCRs are very popular with only a minimum of endeavor and offer a wealth of products.1 The 1,3-oxazine ring system has a structure which known as one of biologically-active heterocycles.2 In addition, realizing the importance of naphthoxine compounds which has alterative prospect for the treatment of Parkinson’s disease reported.3 Previously, some is shown in protocols for synthesis of various naphtho[1,3]oxazines via a Mannich type condensation between a 2-naphthol, formaldehyde and a primary amine were reported. In this work, we wish to report effective and eco-friendly procedure for the synthesis of 2-aryl/alkyl-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazine in the presence of nano-Al2O3/BF3/Fe3O4. The obtained 1,3-oxazine compounds were characterized by various methods such as FT-IR, 1HNMR and melting point.4
Keywords:
Authors
Elaheh Babaei,
Department of Chemistry, Faculty of Science, Yazd University, Yazd, Iran
Bi Bi Fatemeh Mirjalili
Department of Chemistry, Faculty of Science, Yazd University, Yazd, Iran