Some parameters of intestinal barrier damage response to high-intensity intervals in comparison to continuous moderate training

The term, “exercise-induced gastrointestinal syndrome”, has recently been introduced to describe a complex array of normal physiological responses to exercise that perturbs and compromises gastrointestinal integrity and function. Thus, because of the ambiguities about the exercise-induced gastrointestinal disorders, especially high-intensity intermittent exercise (HIIT) the present study investigated to compare the responses of Immunoglobulin M and some gastrointestinal disorders markers to one-session continuous moderate training and high-intensity interval training (MICT & HIIT) in female athletes.To investigate the response of indicators related to the gastrointestinal syndrome, in a quasi-experimental design, thirty female athletes participated in three equal groups (MICT: n=۱۰, HIIT: n=۱۰, and control: n=۱۰). MICT consisted of ۶۰ minutes’ submaximal steady-state running at ۷۰% heart rate reserve, and HIIT athletes completed an acute bout of running (eighteen ۴۰۰ m runs at maximum speed). Blood samples were collected before, immediately, and two h after the exercise protocols. I-FABP, zonulin, LPS, and IgM amounts were measured using ELISA methods. All data expressed as mean±SD and analyzed using repeated-measures analysis of variance at α≤۰.۰۵.Levels of I-FABP, LPS, and zonulin increased significantly (p<۰.۰۵) after MICT and HIIT protocols, whereas Ig-M concentration decreased significantly (p<۰.۰۵). However, the significant difference between acute decreased IgM responses and increased I-FABP, LPS, and zonulin responses to one-session MICT and HIIT protocols were not observed (p>۰.۰۵).Based on the results of the present study, it can conclude that the acute gastrointestinal (GI) responses in female athletes to one-session MICT and HIIT protocols may similarly increase GI permeability, intestinal damage, and endotoxemia.

Keywords:

intense intermittent exercise , intestinal damage , intestinal permeability