study of electrospun poly(caprolacton)-chitosan and antimicrobial properties

Natural polymers in terms of the environmental characteristics and their compatibility with the human body have vast applications in the industry: cosmetics, wound dressing, delivery of medicine scaffold, and so on. In this study, antimicrobia properties PCL-chitosan nanofibers that a biocompatible polymer packag will be examine.For this purpose, first the nanofibers made of PCL-chitosan-with optimal concentration of the polymers was produced by electrospinning. The surface morphology of nanofibers microscopy (SEM) were studied. Using infrared spectrometer instrument (FTIR) evaluated the link poly(caprolacton)-chitosan in nano-fibers. The effect of antimicrobial from nanofibers with standard (AATCC100) measurement and determined.According to antimicrobial test the nano-fiber manufacturing against Gram-positive and Gram-negative bacteria, Escherichia coli and Staphylococcus Cocos considerable influence along.Based on the results of tests it was found that nano-fiber PCL-chitosan with a ratio of 80-20 and a concentration of 1 gr and 0.5gr, Most antimicrobial effect itself show compared to concentrations and the other ratios. In total we had a good antimicrobial effect.

Keywords:

: electrospinning , poly-caprolactone , chitosan , antimicrobial