Synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives in the presence of a magnetic ionic liquid catalyst

Dihydroquinazolin-4(1H)-one derivatives are an important class of heterocyclic compounds that possess important biological, pharmacological and physiological activities.1 Using multicomponent reactions (MCRs) for the synthesis of organic compounds accompanied with economic and ecological insight is highly valuable.2 On the other hands, ionic liquids as designable solvents, reagents and/or catalysts had been used for various purposes.3 In this study, we would like to report the synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives via one-pot three-component reaction of arylaldehydes, 2-aminobenzothiazole and isatoic anhydride in the presence of magnetic ionic liquid as a highly efficient catalyst at 80 oC under solvent-free conditions. The structure of products were approved on the basis of their physical data , IR spectroscopic, 1H and 13C NMR.

Keywords:

Multicomponent reactions , Dihydroquinazolin-4(1H)-ones , Magnetic ionic liquid